Regression in Down Syndrome. Case Study of a Young Adult With Down Syndrome Who Was Referred to Brent Community Learning Disability Service With ‘Unexplained’ Changes in Behaviour

Aims There has been growing interest in regression among adolescents and young adults with Down Syndrome. Regression can also be referred to Acute Regression, Syndrome Disorder (DSRD), Disintegrative disorder (DSDD) or Unexplained (URDS) these terms are sometimes used interchangeably. Characterised by reduction expressive language, decreased functional skills reduced psychomotor activity, result a significant change the long-term needs of individuals. Reporting this case, we wanted highlight challenges diagnosing, treating supporting people Methods This is Case Study adult presenting symptoms mood disorder, apathy, new-onset vocal tics ritualistic behaviours profound loss language - both verbal sign language. Results Diagnosis included ruling out physical causes for regression. The management remains largely symptomatic aims address as many possible bio-psycho-social aspects concerning presentation. Conclusion Multitude interventions external events made it difficult see what intervention was most useful. Despite initial positive response medication behavioural strategies, long term prognosis uncertain.